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locomotor exercise assessments in mice. Our results demonstrate that eutylone is often a powerful DAT uptake inhibitor with behavioral effects comparable to pentylone.
.eleven, 13, 21, 41 The conclusions documented here for dibutylone in mice don't concur Along with the Idea that high DAT/SERT ratio governs stimulant Houses since dibutylone had the very best DAT/SERT ratio but least expensive potency to induce locomotor activity. Then again, the activity of pentylone and eutylone at SERT proven below might be to blame for drug-induced stereotypies which tend to cut back forward locomotion, as dibutylone did not produce this influence within our scientific studies.
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